24 Hour Urgent Care in Durham, NC
Durham urgent care centers serve the City of Medicine — a nickname earned through the extraordinary concentration of world-class health institutions including Duke University Health System, the Durham VA Medical Center, and the Research Triangle Park, the largest research park in the United States straddling Durham, Orange, and Wake counties and home to tens of thousands of biotech, pharmaceutical, and technology workers. Walk-in clinics along Surles Court, Nc Highway 751, and North Roxboro Road provide same-day care to an unusually well-educated, research-oriented population of Duke employees, RTP workers, and the diverse Durham community that has gentrified Bull City neighborhoods like Brightleaf and the American Tobacco Campus, all anchored medically by Duke University Hospital in one of the South's most medically sophisticated urgent care markets.
Urgent care hours in Durham, NC: The earliest opening time among Durham, NC's 10 listed urgent care clinics is 8am, and the latest closing time is 8pm. 0 locations stay open past 9pm, and 7 are open on weekends — use the Open Now filter below to see who's currently accepting patients.
Filter clinics:
Duke Urgent Care Croasdaile
Carolina Urgent CareCall to Confirm
Duke Urgent Care South
FastMed Urgent Care
AFC Urgent Care Southpoint
WakeMed MyCare 365 Primary & Urgent Care - Lowes Grove
New Hope Urgent Care
WakeMed MyCare 365 Primary & Urgent Care - Hope Valley
Concentra Urgent CareCall to Confirm
Duke Urgent Care Center: Kann Joel R MDCall to Confirm
What to Expect at Urgent Care in Durham, NC
Listings are checked against Google's Places API and, where needed, the CMS NPPES provider registry — see how we verify listings. Hours change frequently, so please call ahead to confirm before visiting. Found an error? Let us know.
Health Considerations in North Carolina
The Research Triangle region of North Carolina — Raleigh, Durham, and Chapel Hill — is notorious for extreme spring pollen seasons, with tree pollen counts among the highest in the country from late February through April, driving heavy urgent care demand for allergy symptoms, sinus infections, and asthma flares. The state's coastal communities also face hurricane risk, and summer heat and humidity in the Piedmont and coastal plain create conditions for heat-related illness from June through September.
Urgent Care in Durham, NC — Frequently Asked Questions
Is urgent care open on weekends in Durham, NC?
Yes — 7 of the 10 urgent care centers listed above for Durham, NC are open on Saturdays and Sundays. Some locations have reduced Sunday hours, so check the listings above for exact weekend hours at each clinic. If you need care on a Sunday evening, it's worth calling ahead to confirm the location hasn't closed early.
Do I need an appointment for urgent care in Durham, NC?
No appointment is needed at most Durham, NC urgent care centers. Walk-ins are welcome at all locations listed above. Some clinics offer online check-in so you can hold your spot in line before you arrive and reduce your time in the waiting room — check the clinic's website or Google listing to see if this is available.
How much does urgent care cost in Durham, NC?
A typical urgent care visit in Durham, NC costs between $100 and $200 without insurance for a basic exam. Additional services — such as X-rays, lab tests, rapid strep or flu tests, or stitches — will increase the total. Most clinics will provide a cost estimate when you call, and many post their self-pay rates on their website. See our full urgent care cost guide for a detailed breakdown.
Does urgent care in Durham, NC accept Medicaid?
Many urgent care centers in Durham, NC accept North Carolina Medicaid along with Medicare and major commercial insurance plans, but acceptance varies by clinic and by Medicaid managed-care plan. Call ahead to confirm the location takes your specific plan and is in-network before your visit.
What is the wait time at urgent care in Durham, NC?
Wait times vary by clinic. WakeMed MyCare 365 Primary & Urgent Care - Lowes Grove is the highest-rated option among the 10 clinics listed here, at 4.9★. Weekday mornings tend to have the shortest waits industry-wide, and online check-in — where available — can reduce time in the waiting room.
What can urgent care treat in Durham, NC?
Durham, NC urgent care centers treat a wide range of non-life-threatening conditions including colds, flu, strep throat, ear infections, urinary tract infections, minor cuts and lacerations, sprains, rashes, pink eye, and more. Many locations also provide X-rays, lab work, and vaccinations. For chest pain, difficulty breathing, stroke symptoms, or other emergencies, go to the nearest ER or call 911.
Should I go to urgent care or the ER in Durham, NC?
Choose urgent care for non-life-threatening conditions — infections, minor injuries, illness, and anything that isn't immediately dangerous. Go to the ER (or call 911) for chest pain, difficulty breathing, suspected stroke, severe bleeding, loss of consciousness, or any situation that could be life-threatening. Urgent care is typically faster and far less expensive for the conditions it's designed to handle. See our full ER vs. urgent care guide for more detail.
How many urgent care options does Durham, NC have?
Durham, NC has 10 listed urgent care clinics, averaging 4.3★ across 6,579 reviews. See the full list above for addresses, phone numbers, and hours.