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24 Hour Urgent Care in O'Fallon, MO

O'Fallon is the largest city in St. Charles County and one of the most rapidly growing municipalities in the greater St. Louis metro, served by SSM Health and BJC HealthCare with urgent care clinics along Highway K, Clay Street, and Veterans Memorial Parkway. The city's young family population, booming residential construction, and expanding commercial corridors create exceptionally high urgent care demand, and its position along I-64 makes it accessible to patients from across western St. Charles County.

Urgent care hours in O'Fallon, MO: The earliest opening time among O'Fallon, MO's 6 listed urgent care clinics is 8am, and the latest closing time is 8pm. 0 locations stay open past 9pm, and 6 are open on weekends — use the Open Now filter below to see who's currently accepting patients.

3.8★
Avg. rating across 3,226 reviews
0 of 6
Clinics open until 9pm or later
6 of 6
Clinics open on weekends
4.9★
Top-rated: Total Access Urgent Care - O'Fallon South

Filter clinics:

★ 3.8 avg Google rating6 of 6 clinics ratedMedicaid & Medicare accepted at many locations; call to confirm
⚠️Always call ahead to verify hours and availability. Clinic information on this site may be outdated or inaccurate. Do not rely solely on this listing — confirm directly with the clinic before visiting. For medical emergencies, call 911.
ℹ️Insurance & Medicaid: Many urgent care centers accept Medicaid, Medicare, and major PPO/HMO plans, but it varies by clinic and by plan. Coverage varies by location — call ahead to confirm your specific plan is accepted before your visit.

Total Access Urgent Care - O'Fallon NorthOpen Now

★★★★½4.7(1,437 reviews)Google reviews ↗
Address: 507 S Main St, O'Fallon, MO 63366
Hours: Sun–Sat 8am–8pm

BJC Medical Group Convenient Care at O'FallonOpen Now

★★★☆☆3.4(110 reviews)Google reviews ↗
Address: 2630 State Hwy K, O'Fallon, MO 63368
Hours: Sun–Sat 8am–8pm
Website: bjc.org

Total Access Urgent Care - O'Fallon SouthOpen Now

★★★★½4.9(1,116 reviews)Google reviews ↗
Address: 4201 State Hwy K, O'Fallon, MO 63368
Hours: Sun–Sat 8am–8pm

St. Luke's Urgent Care Center - O'FallonOpen Now

★★½☆☆2.9(137 reviews)Google reviews ↗
Address: 5551 Winghaven Blvd Suite 100, O'Fallon, MO 63368
Hours: Sun–Sat 8am–8pm

SSM Health Urgent CareOpen Now

★★½☆☆2.6(27 reviews)Google reviews ↗
Address: 301 Caledonia Pkwy Ste 120, O'Fallon, MO 63368
Hours: Sun–Sat 8am–8pm
Insurance this chain generally accepts: Most major insurance, Medicare, Medicaid (varies by location, call to confirm)
Services:
Urgent careLab testingX-rayVirtual care

Mercy-GoHealth Urgent CareOpen Now

★★★★☆4.1(399 reviews)Google reviews ↗
Address: 2991 State Hwy K, O'Fallon, MO 63368
Hours: Sun 9am–5pm, Mon–Fri 8am–8pm, Sat 9am–5pm

What to Expect at Urgent Care in O'Fallon, MO

Typical Cost
$100–$200
Without insurance for a basic exam. X-rays, labs, or stitches add to the total. Many clinics post self-pay rates online.
Average Wait
15–45 min
O'Fallon, MO has 6 listed clinics. Weekday mornings tend to have the shortest waits — use online check-in where available.
What to Bring
ID & Insurance Card
Photo ID, insurance card, and a list of current medications and known allergies. Most clinics also accept walk-ins without prior paperwork.
When to Go to the ER
Chest pain, stroke signs, or major trauma
Urgent care is for non-life-threatening conditions only. For emergencies, call 911 or go directly to the nearest emergency room.

Listings are checked against Google's Places API and, where needed, the CMS NPPES provider registry — see how we verify listings. Hours change frequently, so please call ahead to confirm before visiting. Found an error? Let us know.

Health Considerations in Missouri

Missouri sits at the intersection of several climate zones, producing extreme weather across the seasons: tornado activity is significant in spring, summer heat and humidity can be intense, and Arctic air masses bring severe winter conditions across the state. The St. Louis and Kansas City metro areas have strong urgent care networks, while rural parts of the state face healthcare access challenges that make urgent care centers in regional hubs critical for residents across large geographic areas.

Urgent Care in O'Fallon, MO — Frequently Asked Questions

Is urgent care open on weekends in O'Fallon, MO?

Yes — 6 of the 6 urgent care centers listed above for O'Fallon, MO are open on Saturdays and Sundays. Some locations have reduced Sunday hours, so check the listings above for exact weekend hours at each clinic. If you need care on a Sunday evening, it's worth calling ahead to confirm the location hasn't closed early.

Do I need an appointment for urgent care in O'Fallon, MO?

No appointment is needed at most O'Fallon, MO urgent care centers. Walk-ins are welcome at all locations listed above. Some clinics offer online check-in so you can hold your spot in line before you arrive and reduce your time in the waiting room — check the clinic's website or Google listing to see if this is available.

How much does urgent care cost in O'Fallon, MO?

A typical urgent care visit in O'Fallon, MO costs between $100 and $200 without insurance for a basic exam. Additional services — such as X-rays, lab tests, rapid strep or flu tests, or stitches — will increase the total. Most clinics will provide a cost estimate when you call, and many post their self-pay rates on their website. See our full urgent care cost guide for a detailed breakdown.

Does urgent care in O'Fallon, MO accept Medicaid?

Many urgent care centers in O'Fallon, MO accept Missouri Medicaid along with Medicare and major commercial insurance plans, but acceptance varies by clinic and by Medicaid managed-care plan. Call ahead to confirm the location takes your specific plan and is in-network before your visit.

What is the wait time at urgent care in O'Fallon, MO?

Wait times vary by clinic. Total Access Urgent Care - O'Fallon South is the highest-rated option among the 6 clinics listed here, at 4.9★. Weekday mornings tend to have the shortest waits industry-wide, and online check-in — where available — can reduce time in the waiting room.

What can urgent care treat in O'Fallon, MO?

O'Fallon, MO urgent care centers treat a wide range of non-life-threatening conditions including colds, flu, strep throat, ear infections, urinary tract infections, minor cuts and lacerations, sprains, rashes, pink eye, and more. Many locations also provide X-rays, lab work, and vaccinations. For chest pain, difficulty breathing, stroke symptoms, or other emergencies, go to the nearest ER or call 911.

Should I go to urgent care or the ER in O'Fallon, MO?

Choose urgent care for non-life-threatening conditions — infections, minor injuries, illness, and anything that isn't immediately dangerous. Go to the ER (or call 911) for chest pain, difficulty breathing, suspected stroke, severe bleeding, loss of consciousness, or any situation that could be life-threatening. Urgent care is typically faster and far less expensive for the conditions it's designed to handle. See our full ER vs. urgent care guide for more detail.

How many urgent care options does O'Fallon, MO have?

O'Fallon, MO has 6 listed urgent care clinics, averaging 3.8★ across 3,226 reviews. See the full list above for addresses, phone numbers, and hours.

Urgent Care Guides & Resources

24 Hour Urgent Care Near Me — Find Open ClinicsER vs. Urgent Care — Which Should You Choose?How Much Does Urgent Care Cost?Walk-In vs. Appointment — What to KnowWhat to Bring to Urgent CareUrgent Care vs. TelehealthUrgent Care for Flu & ColdUrgent Care for Strep ThroatUrgent Care for UTIsUrgent Care for Pink EyeUrgent Care for Ear InfectionsUrgent Care for Cuts & StitchesUrgent Care for Sprained AnklesUrgent Care for Fever in ChildrenDOT Physicals at Urgent CareSTD Testing at Urgent CareIV Hydration TherapyPediatric Urgent Care for KidsSports Injury & Orthopedic CareOccupational Health & Drug Testing

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