24 Hour Urgent Care in Port St. Lucie, FL
Port St. Lucie urgent care centers serve the Treasure Coast's largest city in St. Lucie County, one of Florida's fastest-growing metros where walk-in clinics along Gatlin Boulevard, Federal Highway, and NW Courtyard Circle provide same-day care to an expanding population of retirees, young families, and workers drawn by affordable housing compared to Miami and Palm Beach. Anchored medically by Cleveland Clinic Martin Health and Lawnwood Regional Medical Center, Port St. Lucie's urgent care market has exploded alongside the city's growth from a sleepy planned community into a major South Florida metro, serving snowbirds wintering near the St. Lucie River and permanent residents who commute south along I-95 to the Palm Beaches.
Urgent care hours in Port St. Lucie, FL: The earliest opening time among Port St. Lucie, FL's 10 listed urgent care clinics is 8am, and the latest closing time is 10pm. 1 location stays open past 9pm, and 8 are open on weekends — use the Open Now filter below to see who's currently accepting patients.
Filter clinics:
CareSpot Urgent Care of Port St. Lucie
MD Now Urgent Care - Port St. Lucie East
MD Now Urgent Care - St. Lucie West
Access 365 Urgent CareCall to Confirm
MD Now Urgent Care - Port St. Lucie Southwest
MD Now Urgent Care - Tradition
PM Pediatric Urgent Care (Formerly Night Lite Pediatrics)
Xpress Urgent Care - Port St. Lucie East
MinuteClinic at CVSCall to Confirm
Vital Health Center - Port St. Lucie
What to Expect at Urgent Care in Port St. Lucie, FL
Listings are checked against Google's Places API and, where needed, the CMS NPPES provider registry — see how we verify listings. Hours change frequently, so please call ahead to confirm before visiting. Found an error? Let us know.
Health Considerations in Florida
Florida's subtropical climate creates two dominant urgent care seasons: summer heat illness peaks from June through September as humidity and temperatures combine to cause dehydration, heat cramps, and heat exhaustion — especially in older adults — and respiratory illness season spikes in winter when the state's large snowbird population concentrates in coastal communities. Florida's coastal geography also brings hurricane-related trauma and stress-related presentations during active storm seasons, and the year-round outdoor lifestyle increases skin infections, insect bites, and marine-related injuries for both residents and tourists.
Urgent Care in Port St. Lucie, FL — Frequently Asked Questions
Is urgent care open on weekends in Port St. Lucie, FL?
Yes — 8 of the 10 urgent care centers listed above for Port St. Lucie, FL are open on Saturdays and Sundays. Some locations have reduced Sunday hours, so check the listings above for exact weekend hours at each clinic. If you need care on a Sunday evening, it's worth calling ahead to confirm the location hasn't closed early.
Do I need an appointment for urgent care in Port St. Lucie, FL?
No appointment is needed at most Port St. Lucie, FL urgent care centers. Walk-ins are welcome at all locations listed above. Some clinics offer online check-in so you can hold your spot in line before you arrive and reduce your time in the waiting room — check the clinic's website or Google listing to see if this is available.
How much does urgent care cost in Port St. Lucie, FL?
A typical urgent care visit in Port St. Lucie, FL costs between $100 and $200 without insurance for a basic exam. Additional services — such as X-rays, lab tests, rapid strep or flu tests, or stitches — will increase the total. Most clinics will provide a cost estimate when you call, and many post their self-pay rates on their website. See our full urgent care cost guide for a detailed breakdown.
Does urgent care in Port St. Lucie, FL accept Medicaid?
Many urgent care centers in Port St. Lucie, FL accept Florida Medicaid along with Medicare and major commercial insurance plans, but acceptance varies by clinic and by Medicaid managed-care plan. Call ahead to confirm the location takes your specific plan and is in-network before your visit.
What is the wait time at urgent care in Port St. Lucie, FL?
Wait times vary by clinic. CareSpot Urgent Care of Port St. Lucie is the highest-rated option among the 10 clinics listed here, at 4.5★. 1 of 10 stay open past 9pm for after-work visits. Weekday mornings tend to have the shortest waits industry-wide, and online check-in — where available — can reduce time in the waiting room.
What can urgent care treat in Port St. Lucie, FL?
Port St. Lucie, FL urgent care centers treat a wide range of non-life-threatening conditions including colds, flu, strep throat, ear infections, urinary tract infections, minor cuts and lacerations, sprains, rashes, pink eye, and more. Many locations also provide X-rays, lab work, and vaccinations. For chest pain, difficulty breathing, stroke symptoms, or other emergencies, go to the nearest ER or call 911.
Should I go to urgent care or the ER in Port St. Lucie, FL?
Choose urgent care for non-life-threatening conditions — infections, minor injuries, illness, and anything that isn't immediately dangerous. Go to the ER (or call 911) for chest pain, difficulty breathing, suspected stroke, severe bleeding, loss of consciousness, or any situation that could be life-threatening. Urgent care is typically faster and far less expensive for the conditions it's designed to handle. See our full ER vs. urgent care guide for more detail.
How many urgent care options does Port St. Lucie, FL have?
Port St. Lucie, FL has 10 listed urgent care clinics, averaging 4.3★ across 9,028 reviews. See the full list above for addresses, phone numbers, and hours.