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24 Hour Urgent Care in Sioux City, IA

Sioux City urgent care centers serve the largest city in western Iowa and the commercial hub of the Missouri River tri-state region where Iowa, Nebraska, and South Dakota converge, anchored by MercyOne and UnityPoint Health with walk-in clinics along Sergeant Road. The city's meatpacking and food processing industry anchors including Tyson Foods and IBP, large Hispanic immigrant workforce, and role as the medical center for a broad rural tri-state catchment area create an urgent care market shaped by occupational health needs and a population that spans multiple states and income levels.

Urgent care hours in Sioux City, IA: The earliest opening time among Sioux City, IA's 2 listed urgent care clinics is 8am, and the latest closing time is 8pm. 0 locations stay open past 9pm, and 2 are open on weekends — use the Open Now filter below to see who's currently accepting patients.

3.5★
Avg. rating across 86 reviews
0 of 2
Clinics open until 9pm or later
2 of 2
Clinics open on weekends
3.8★
Top-rated: UnityPoint Clinic Urgent Care - Marketplace

Filter clinics:

★ 3.5 avg Google rating2 of 2 clinics ratedMedicaid & Medicare accepted at many locations; call to confirm
⚠️Always call ahead to verify hours and availability. Clinic information on this site may be outdated or inaccurate. Do not rely solely on this listing — confirm directly with the clinic before visiting. For medical emergencies, call 911.
ℹ️Insurance & Medicaid: Many urgent care centers accept Medicaid, Medicare, and major PPO/HMO plans, but it varies by clinic and by plan. Coverage varies by location — call ahead to confirm your specific plan is accepted before your visit.

UnityPoint Clinic Urgent Care - SunnybrookOpen Now

★★★☆☆3.2(69 reviews)Google reviews ↗
Address: 5885 Sunnybrook Dr, Sioux City, IA 51106
Hours: Sun 8am–6pm, Mon–Fri 9am–8pm, Sat 8am–6pm

UnityPoint Clinic Urgent Care - MarketplaceOpen Now

★★★½☆3.8(17 reviews)Google reviews ↗
Address: 3035 Hamilton Blvd, Sioux City, IA 51104
Hours: Sun 9am–1pm, Mon 9am–8pm, Tue 1pm–8pm, Wed 9am–5pm, Thu 1pm–8pm, Fri 9am–8pm, Sat 9am–1pm

What to Expect at Urgent Care in Sioux City, IA

Typical Cost
$100–$200
Without insurance for a basic exam. X-rays, labs, or stitches add to the total. Many clinics post self-pay rates online.
Average Wait
15–45 min
Sioux City, IA has 2 listed clinics. Weekday mornings tend to have the shortest waits — use online check-in where available.
What to Bring
ID & Insurance Card
Photo ID, insurance card, and a list of current medications and known allergies. Most clinics also accept walk-ins without prior paperwork.
When to Go to the ER
Chest pain, stroke signs, or major trauma
Urgent care is for non-life-threatening conditions only. For emergencies, call 911 or go directly to the nearest emergency room.

Listings are checked against Google's Places API and, where needed, the CMS NPPES provider registry — see how we verify listings. Hours change frequently, so please call ahead to confirm before visiting. Found an error? Let us know.

Health Considerations in Iowa

Iowa's agricultural economy means occupational injuries from farming equipment, grain handling, and livestock are a notable driver of urgent care visits, particularly in rural communities with limited access to specialty orthopedic or trauma care. Extreme weather is also a factor: Iowa sits in tornado alley and experiences both harsh winters and hot, humid summers, with seasonal respiratory illness and heat-related conditions common at opposite ends of the calendar.

Urgent Care in Sioux City, IA — Frequently Asked Questions

Is urgent care open on weekends in Sioux City, IA?

Yes — 2 of the 2 urgent care centers listed above for Sioux City, IA are open on Saturdays and Sundays. Some locations have reduced Sunday hours, so check the listings above for exact weekend hours at each clinic. If you need care on a Sunday evening, it's worth calling ahead to confirm the location hasn't closed early.

Do I need an appointment for urgent care in Sioux City, IA?

No appointment is needed at most Sioux City, IA urgent care centers. Walk-ins are welcome at all locations listed above. Some clinics offer online check-in so you can hold your spot in line before you arrive and reduce your time in the waiting room — check the clinic's website or Google listing to see if this is available.

How much does urgent care cost in Sioux City, IA?

A typical urgent care visit in Sioux City, IA costs between $100 and $200 without insurance for a basic exam. Additional services — such as X-rays, lab tests, rapid strep or flu tests, or stitches — will increase the total. Most clinics will provide a cost estimate when you call, and many post their self-pay rates on their website. See our full urgent care cost guide for a detailed breakdown.

Does urgent care in Sioux City, IA accept Medicaid?

Many urgent care centers in Sioux City, IA accept Iowa Medicaid along with Medicare and major commercial insurance plans, but acceptance varies by clinic and by Medicaid managed-care plan. Call ahead to confirm the location takes your specific plan and is in-network before your visit.

What is the wait time at urgent care in Sioux City, IA?

Wait times vary by clinic. UnityPoint Clinic Urgent Care - Marketplace is the highest-rated option among the 2 clinics listed here, at 3.8★. Weekday mornings tend to have the shortest waits industry-wide, and online check-in — where available — can reduce time in the waiting room.

What can urgent care treat in Sioux City, IA?

Sioux City, IA urgent care centers treat a wide range of non-life-threatening conditions including colds, flu, strep throat, ear infections, urinary tract infections, minor cuts and lacerations, sprains, rashes, pink eye, and more. Many locations also provide X-rays, lab work, and vaccinations. For chest pain, difficulty breathing, stroke symptoms, or other emergencies, go to the nearest ER or call 911.

Should I go to urgent care or the ER in Sioux City, IA?

Choose urgent care for non-life-threatening conditions — infections, minor injuries, illness, and anything that isn't immediately dangerous. Go to the ER (or call 911) for chest pain, difficulty breathing, suspected stroke, severe bleeding, loss of consciousness, or any situation that could be life-threatening. Urgent care is typically faster and far less expensive for the conditions it's designed to handle. See our full ER vs. urgent care guide for more detail.

How many urgent care options does Sioux City, IA have?

Sioux City, IA has 2 listed urgent care clinics, averaging 3.5★ across 86 reviews. See the full list above for addresses, phone numbers, and hours.

Urgent Care Guides & Resources

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