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24 Hour Urgent Care in South Carolina

Find 24 hour urgent care clinics across South Carolina — open now with no appointment needed. Browse 15 cities below to see clinic locations, hours, insurance and Medicaid acceptance, and contact info for same-day and late-night care.

Urgent Care by City in South Carolina (15)

Anderson →Beaufort →Charleston, SC →Columbia →Florence, SC →Goose Creek, SC →Greenville →Hilton Head Island, SC →Mount Pleasant, SC →Myrtle Beach →North Charleston, SC →Rock Hill, SC →Spartanburg →Summerville, SC →Sumter →

About Urgent Care in South Carolina

Appointment needed
Usually not — most locations take walk-ins
Insurance
Many accept South Carolina Medicaid, Medicare, and major PPO/HMO plans; call to confirm
Typical cost
$100–$200 without insurance for a basic exam
Conditions treated
Cold, flu, injuries, infections, rashes, UTIs, and more

Health Considerations in South Carolina

South Carolina's subtropical coastal climate — particularly in Charleston, Hilton Head, and the Grand Strand — creates year-round heat and humidity that make heat exhaustion, dehydration, and skin infections common during the long summer season. The state's hurricane exposure on the Atlantic coast also creates periodic storm-related urgent care surges, and high spring and summer pollen counts drive significant allergy and sinus infection presentations across the Upstate and Midlands regions.

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