24 Hour Urgent Care in Tupelo
Tupelo is the county seat of Lee County and the birthplace of Elvis Presley, serving as the commercial and medical hub of northeast Mississippi. North Mississippi Medical Center, the largest non-metropolitan hospital in the country at 640 beds, is a Level II trauma center that draws patients from 24 counties across north Mississippi, northwest Alabama, and southern Tennessee; urgent care centers on North Coley Road serve Tupelo's own population alongside patients from smaller communities throughout Lee, Pontotoc, and Union counties.
Urgent care hours in Tupelo: The earliest opening time among Tupelo's 9 listed urgent care clinics is 7am, and the latest closing time is 7pm. 0 locations stay open past 9pm, and 4 are open on weekends — use the Open Now filter below to see who's currently accepting patients.
Filter clinics:
Barnes Crossing Urgent CareCall to Confirm
Express Care Clinic
MedPlus Urgent Clinic
Fast Pace Health Urgent Care - Tupelo - MS
West Tupelo Urgent CareCall to Confirm
Verona Family Medicine and Urgent CareCall to Confirm
Express Care West Medical Clinic
ENT Urgent Care Tupelo CrosstownCall to Confirm
Mississippi Sports Medicine Walk-In Clinic (formerly Orthopaedic Institute of North MS Walk-In Clinic)Call to Confirm
What to Expect at Urgent Care in Tupelo
Listings are checked against Google's Places API and, where needed, the CMS NPPES provider registry — see how we verify listings. Hours change frequently, so please call ahead to confirm before visiting. Found an error? Let us know.
Health Considerations in Mississippi
Mississippi's hot, humid Gulf Coast climate makes heat exhaustion and heat-related illness a major summer health concern, particularly in a state where outdoor labor — agricultural, construction, and oil and gas work — remains common. The state ranks among the highest in the country for obesity, diabetes, and cardiovascular risk, which increases the severity of urgent care presentations even for routine illness in a population managing multiple chronic conditions.
Urgent Care in Tupelo — Frequently Asked Questions
Is urgent care open on weekends in Tupelo?
Yes — 4 of the 9 urgent care centers listed above for Tupelo are open on Saturdays and Sundays. Some locations have reduced Sunday hours, so check the listings above for exact weekend hours at each clinic. If you need care on a Sunday evening, it's worth calling ahead to confirm the location hasn't closed early.
Do I need an appointment for urgent care in Tupelo?
No appointment is needed at most Tupelo urgent care centers. Walk-ins are welcome at all locations listed above. Some clinics offer online check-in so you can hold your spot in line before you arrive and reduce your time in the waiting room — check the clinic's website or Google listing to see if this is available.
How much does urgent care cost in Tupelo?
A typical urgent care visit in Tupelo costs between $100 and $200 without insurance for a basic exam. Additional services — such as X-rays, lab tests, rapid strep or flu tests, or stitches — will increase the total. Most clinics will provide a cost estimate when you call, and many post their self-pay rates on their website. See our full urgent care cost guide for a detailed breakdown.
Does urgent care in Tupelo accept Medicaid?
Many urgent care centers in Tupelo accept Mississippi Medicaid along with Medicare and major commercial insurance plans, but acceptance varies by clinic and by Medicaid managed-care plan. Call ahead to confirm the location takes your specific plan and is in-network before your visit.
What is the wait time at urgent care in Tupelo?
Wait times vary by clinic. ENT Urgent Care Tupelo Crosstown is the highest-rated option among the 9 clinics listed here, at 5★. Weekday mornings tend to have the shortest waits industry-wide, and online check-in — where available — can reduce time in the waiting room.
What can urgent care treat in Tupelo?
Tupelo urgent care centers treat a wide range of non-life-threatening conditions including colds, flu, strep throat, ear infections, urinary tract infections, minor cuts and lacerations, sprains, rashes, pink eye, and more. Many locations also provide X-rays, lab work, and vaccinations. For chest pain, difficulty breathing, stroke symptoms, or other emergencies, go to the nearest ER or call 911.
Should I go to urgent care or the ER in Tupelo?
Choose urgent care for non-life-threatening conditions — infections, minor injuries, illness, and anything that isn't immediately dangerous. Go to the ER (or call 911) for chest pain, difficulty breathing, suspected stroke, severe bleeding, loss of consciousness, or any situation that could be life-threatening. Urgent care is typically faster and far less expensive for the conditions it's designed to handle. See our full ER vs. urgent care guide for more detail.
How many urgent care options does Tupelo have?
Tupelo has 9 listed urgent care clinics, averaging 4.5★ across 876 reviews. See the full list above for addresses, phone numbers, and hours.